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Standards Ontologies Notations
Vitamin K-dependent protein C

Summary
UniProt ID
P04070
Gene Symbol
  • PROC
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011352
GlyConnect
GlyGen
P04070
PubChem
P04070
The Human Metabolome Database
HMDBP02002
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • EGF-like domain
  • Endoplasmic reticulum
  • Gamma-carboxyglutamic acid
  • Glycoprotein
  • Golgi apparatus
  • Hydroxylation
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Thrombophilia
  • Zymogen
Gene Ontology (GO)
Displaying all 2 entries
GO Term
serine-type endopeptidase activity
calcium ion binding
Annotation information from UniProt.
Sequence
MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
19 O-linked (GalNAc...) threonine
139
290 N-linked (GlcNAc...) asparagine
355 N-linked (GlcNAc...) asparagine
371 N-linked (GlcNAc...) asparagine; atypical; partial
382
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 8 entries
Pathway Name Organism
Cell surface interactions at the vascular wall Homo sapiens
Common Pathway of Fibrin Clot Formation Homo sapiens
Gamma-carboxylation of protein precursors Homo sapiens
Intrinsic Pathway of Fibrin Clot Formation Homo sapiens
Post-translational protein phosphorylation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
Removal of aminoterminal propeptides from gamma-carboxylated proteins Homo sapiens
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Homo sapiens
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024