toxic shock syndrome

Summary
Synonym
  • TSS
  • toxic shock
Definition
A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
Super Class
commensal bacterial infectious disease
Disease Ontology
DOID:14115
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 37 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
133 ADM adrenomedullin
154 ADRB2 adrenoceptor beta 2
462 SERPINC1 serpin family C member 1
710 SERPING1 serpin family G member 1
887 CCKBR cholecystokinin B receptor
1636 ACE angiotensin I converting enzyme
1991 ELANE elastase, neutrophil expressed
2026 ENO2 enolase 2
2147 F2 coagulation factor II, thrombin
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11555 Adrb2 adrenergic receptor, beta 2
11905 Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
12258 Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1
12426 Cckbr cholecystokinin B receptor
13807 Eno2 enolase 2, gamma neuronal
14061 F2 coagulation factor II
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
15978 Ifng interferon gamma
16153 Il10 interleukin 10
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
24153 A2m alpha-2-macroglobulin
24310 Ace angiotensin I converting enzyme
24334 Eno2 enolase 2
24472 Hspa1a heat shock protein family A (Hsp70) member 1A
24617 Serpine1 serpin family E member 1
24715 Ren renin
24770 Ccl2 C-C motif chemokine ligand 2
24816 Tbxa2r thromboxane A2 receptor
24835 Tnf tumor necrosis factor
25268 Proc protein C, inactivator of coagulation factors Va and VIIIa
Displaying all 8 entries
Gene ID Gene Symbol Description Source
33351 Eno Enolase
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
41549 Octbeta2R Octopamine beta2 receptor
45815 Spn27A Serpin 27A
49804 Spn88Ea Serpin 88Ea
49808 Spn42Dd Serpin 42Dd
Displaying 1 entry
Gene ID Gene Symbol Description Source
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
174423 enol-1 Enolase
178585 srp-1 Serpin domain-containing protein
178672 srp-3 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
180251 asp-1 Aspartic protease 1
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying all 6 entries
Gene ID Gene Symbol Description Source
853169 ENO1 phosphopyruvate hydratase ENO1
854575 ERR1 phosphopyruvate hydratase ERR1
855373 ERR3 phosphopyruvate hydratase ERR3
855848 ERR2 phosphopyruvate hydratase ERR2
855949 PEP4 proteinase A
856579 ENO2 phosphopyruvate hydratase ENO2

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