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Cytochrome P450 1A2

Summary

UniProt ID

P04799

Gene Symbol

Cyp1a2
Cyp1a-2

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P04799
PubChem: P04799
O-GlcNAcAtlas: P04799

Annotation

Keyword

Direct protein sequencing
Fatty acid metabolism
Glycoprotein
Heme
Lyase
Membrane
Microsome
Monooxygenase
Reference proteome
Sterol metabolism

Gene Ontology (GO)

Displaying entries **1 - 10** of 31 in total

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GO Term
post-embryonic development
regulation of gene expression
lung development
monocarboxylic acid metabolic process
vitamin E metabolic process
porphyrin-containing compound metabolic process
toxin biosynthetic process
monoterpenoid metabolic process
dibenzo-p-dioxin metabolic process
nitroglycerin metabolic process

Displaying **all 2** entries
GO Term
endoplasmic reticulum membrane
intracellular membrane-bounded organelle

Displaying entries **1 - 10** of 13 in total

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GO Term
oxidoreductase activity
demethylase activity
caffeine oxidase activity
nitrite reductase (NO-forming) activity
estrogen 16-alpha-hydroxylase activity
estrogen 2-hydroxylase activity
hydroperoxy icosatetraenoate dehydratase activity
monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Annotation information from UniProt.

Sequence

MAFSQYISLAPELLLATAIFCLVFWVLRGTRTQVPKGLKSPPGPWGLPFIGHMLTLGKNPHLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSVSSCYLEEHVSKEANHLISKFQKLMAEVGHFEPVNQVVESVANVIGAMCFGKNFPRKSEEMLNLVKSSKDFVENVTSGNAVDFFPVLRYLPNPALKRFKNFNDNFVLFLQKTVQEHYQDFNKNSIQDITGALFKHSENYKDNGGLIPQEKIVNIVNDIFGAGFETVTTAIFWSILLLVTEPKVQRKIHEELDTVIGRDRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKECCIFINQWQVNHDEKQWKDPFVFRPERFLTNDNTAIDKTLSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLHQLEFTVPPGVKVDLTPSYGLTMKPRTCEHVQAWPRFSK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
68	O-linked (GlcNAc) serine	24098488	G49108TO	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Aflatoxin activation and detoxification	Rattus norvegicus
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	Rattus norvegicus
Biosynthesis of maresin-like SPMs	Rattus norvegicus
Biosynthesis of protectins	Rattus norvegicus
Methylation	Rattus norvegicus
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Rattus norvegicus
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Rattus norvegicus