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Cytochrome P450 1A2

Summary

UniProt ID

P04799

Gene Symbol

Cyp1a2
Cyp1a-2

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P04799
PubChem: P04799
O-GlcNAcAtlas: P04799

Annotation

Keyword

Direct protein sequencing
Fatty acid metabolism
Glycoprotein
Heme
Lyase
Membrane
Microsome
Monooxygenase
Reference proteome
Sterol metabolism

Gene Ontology (GO)

Displaying entries **1 - 10** of 31 in total

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GO Term
post-embryonic development
regulation of gene expression
lung development
monocarboxylic acid metabolic process
vitamin E metabolic process
porphyrin-containing compound metabolic process
response to immobilization stress
toxin metabolic process
steroid catabolic process
estrogen metabolic process

Displaying **all 2** entries
GO Term
intracellular membrane-bounded organelle
endoplasmic reticulum membrane

Displaying entries **11 - 13** of 13 in total

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GO Term
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
enzyme binding
heme binding

Annotation information from UniProt.

Sequence

MAFSQYISLAPELLLATAIFCLVFWVLRGTRTQVPKGLKSPPGPWGLPFIGHMLTLGKNPHLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSVSSCYLEEHVSKEANHLISKFQKLMAEVGHFEPVNQVVESVANVIGAMCFGKNFPRKSEEMLNLVKSSKDFVENVTSGNAVDFFPVLRYLPNPALKRFKNFNDNFVLFLQKTVQEHYQDFNKNSIQDITGALFKHSENYKDNGGLIPQEKIVNIVNDIFGAGFETVTTAIFWSILLLVTEPKVQRKIHEELDTVIGRDRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKECCIFINQWQVNHDEKQWKDPFVFRPERFLTNDNTAIDKTLSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLHQLEFTVPPGVKVDLTPSYGLTMKPRTCEHVQAWPRFSK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
68	O-linked (GlcNAc) serine	24098488	G49108TO	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Aflatoxin activation and detoxification	Rattus norvegicus
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	Rattus norvegicus
Biosynthesis of maresin-like SPMs	Rattus norvegicus
Biosynthesis of protectins	Rattus norvegicus
Methylation	Rattus norvegicus
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Rattus norvegicus
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Rattus norvegicus