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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
T-cell surface glycoprotein CD4
Summary
- UniProt ID
- P05540
- Gene Symbol
-
- Cd4
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum lumen |
| endoplasmic reticulum membrane |
| external side of plasma membrane |
| cell surface |
| plasma membrane |
| membrane raft |
| GO Term |
|---|
| signaling receptor binding |
| zinc ion binding |
| MHC class II protein complex binding |
| interleukin-16 binding |
| interleukin-16 receptor activity |
| lipid binding |
| coreceptor activity |
| immunoglobulin binding |
| enzyme binding |
| protein kinase binding |
Sequence
MCRGFSFRHLLPLLLLQLSKLLVVTQGKTVVLGKEGGSAELPCESTSRRSASFAWKSSDQKTILGYKNKLLIKGSLELYSRFDSRKNAWERGSFPLIINKLRMEDSQTYVCELENKKEEVELWVFRVTFNPGTRLLQGQSLTLILDSNPKVSDPPIECKHKSSNIVKDSKAFSTHSLRIQDSGIWNCTVTLNQKKHSFDMKLSVLGFASTSITAYKSEGESAEFSFPLNLGEESLQGELRWKAEKAPSSQSWITFSLKNQKVSVQKSTSNPKFQLSETLPLTLQIPQVSLQFAGSGNLTLTLDRGILYQEVNLVVMKVTQPDSNTLTCEVMGPTSPKMRLILKQENQEARVSRQEKVIQVQAPEAGVWQCLLSEGEEVKMDSKIQVLSKGLNQTMFLAVVLGSAFSFLVFTGLCILFCVRCRHQQRQAARMSQIKRLLSEKKTCQCSHRMQKSHNLI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 186 | N-linked (GlcNAc...) asparagine |
|
||
| 297 | N-linked (GlcNAc...) asparagine |
|
||
| 334 |
|
|
||
| 392 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G23863VK
G78059CC
G36191CD
G50045TK
G16828VN
G72735IY
G52064IJ
G81295CK
G08520NM
G33609NS
G39188ZX
G80966KZ
G39213VZ
G06110VR
G55220VL
G60145BJ
G88673AA
G14669DU
G22768VO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Alpha-defensins | Rattus norvegicus |
| Cargo recognition for clathrin-mediated endocytosis | Rattus norvegicus |
| Clathrin-mediated endocytosis | Rattus norvegicus |
| Downstream TCR signaling | Rattus norvegicus |
| Generation of second messenger molecules | Rattus norvegicus |
| Other interleukin signaling | Rattus norvegicus |
| PD-1 signaling | Rattus norvegicus |
| Phosphorylation of CD3 and TCR zeta chains | Rattus norvegicus |
| Translocation of ZAP-70 to Immunological synapse | Rattus norvegicus |
