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Platelet-derived growth factor receptor beta

Summary

UniProt ID

P05622

Gene Symbol

Pdgfrb
Pdgfr
Pdgfr1

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003287
GlyGen: P05622
PubChem: P05622
The O-GlcNAc Database: P05622

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Chemotaxis
Cytoplasmic vesicle
Developmental protein
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Lysosome
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 52 in total

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GO Term
cell chemotaxis
blood vessel development
in utero embryonic development
kidney development
tissue homeostasis
glycosaminoglycan biosynthetic process
signal transduction
positive regulation of cell population proliferation
peptidyl-tyrosine phosphorylation
positive regulation of cell migration

Displaying **all 9** entries
GO Term
nucleus
cytoplasm
plasma membrane
cytoplasmic vesicle
receptor complex
apical plasma membrane
ruffle
cell surface
lysosomal lumen

Displaying **all 8** entries
GO Term
platelet-derived growth factor receptor activity
platelet-derived growth factor beta-receptor activity
ATP binding
platelet-derived growth factor binding
phosphatidylinositol 3-kinase binding
protein tyrosine kinase activity
signaling receptor binding
kinase activity

Annotation information from UniProt.

Sequence

MGLPGVIPALVLRGQLLLSVLWLLGPQTSRGLVITPPGPEFVLNISSTFVLTCSGSAPVMWEQMSQVPWQEAAMNQDGTFSSVLTLTNVTGGDTGEYFCVYNNSLGPELSERKRIYIFVPDPTMGFLPMDSEDLFIFVTDVTETTIPCRVTDPQLEVTLHEKKVDIPLHVPYDHQRGFTGTFEDKTYICKTTIGDREVDSDTYYVYSLQVSSINVSVNAVQTVVRQGESITIRCIVMGNDVVNFQWTYPRMKSGRLVEPVTDYLFGVPSRIGSILHIPTAELSDSGTYTCNVSVSVNDHGDEKAINISVIENGYVRLLETLGDVEIAELHRSRTLRVVFEAYPMPSVLWLKDNRTLGDSGAGELVLSTRNMSETRYVSELILVRVKVSEAGYYTMRAFHEDDEVQLSFKLQVNVPVRVLELSESHPANGEQTIRCRGRGMPQPNVTWSTCRDLKRCPRKLSPTPLGNSSKEESQLETNVTFWEEDQEYEVVSTLRLRHVDQPLSVRCMLQNSMGGDSQEVTVVPHSLPFKVVVISAILALVVLTVISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPVQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRHSNKHCPPSAELYSNALPVGFSLPSHLNLTGESDGGYMDMSKDESIDYVPMLDMKGDIKYADIESPSYMAPYDNYVPSAPERTYRATLINDSPVLSYTDLVGFSYQVANGMDFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARFPGIHSLRSPLDTSSVLYTAVQPNESDNDYIIPLPDPKPDVADEGLPEGSPSLASSTLNEVNTSSTISCDSPLELQEEPQQAEPEAQLEQPQDSGCPGPLAEAEDSFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
44	N-linked (GlcNAc...) asparagine			UniProt GlyGen
88	N-linked (GlcNAc...) asparagine			UniProt GlyGen
102	N-linked (GlcNAc...) asparagine			UniProt GlyGen
214	N-linked (GlcNAc...) asparagine		G32392SM	UniProt GlyGen
291	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
306	N-linked (GlcNAc...) asparagine	19656770	G80920RR	UniProt GlyGen
353	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
370	N-linked (GlcNAc...) asparagine		G90659AW	GlycoProtDB UniProt GlyGen
444	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
467	N-linked (GlcNAc...) asparagine	19656770	G60834IK	GlycoProtDB UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Downstream signal transduction	Mus musculus
PI3K/AKT Signaling	Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
Signaling by PDGF	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements