Downstream signal transduction

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PDGF:Phospho-PDGF receptor dimerPDGF:Phospho-PDGF receptor dimer:PI3KPI3KATPPIP3PIP2ADPPLCG1PDGF:Phospho-PDGF receptor dimer:PLC-gammaPDGF:p-PDGFR dimer:p-PLCgammaQ62077PDGF:Phospho-PDGF receptor dimer:MyrG-SRCP05480PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRCPDGF:Phospho-PDGF receptor dimer:SHP2PTPN11Phospho PDGF beta receptor: PDGF chain B homodimerPhospho-beta receptor homodimer:GAPRasa1GRB2-1:SOS1PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1GTPGDPp21 RAS:GDPp21 RAS:GTPSTAT family membersPDGF:phospho-PDGF receptor dimer:STATPDGF:Phospho-PDGF receptor dimer:CrkCRK, CRKLBcar1PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3GQ3UHC1PDGF:Phospho-PDGFR receptor dimer:NckNCK1,NCK2PDGF:Phospho-PDGF receptor dimer:Grb7Grb7
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025