Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Insulin receptor
Summary
- UniProt ID
- P06213
- Gene Symbol
-
- INSR
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011401
- GlyConnect
- GlyGen
- P06213
- PubChem
- P06213
- The Human Metabolome Database
- HMDBP01521
- The O-GlcNAc Database
- P06213
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Carbohydrate metabolism
- Cell membrane
- Cleavage on pair of basic residues
- Diabetes mellitus
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Lysosome
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- S-nitrosylation
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| lysosome |
| plasma membrane |
| insulin receptor complex |
| membrane |
| axon |
| dendrite membrane |
| receptor complex |
| extracellular exosome |
| caveola |
| endosome membrane |
Sequence
MATGGRRGAAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 541 | N-linked (GlcNAc...) asparagine | |||
| 633 | N-linked (GlcNAc...) asparagine | |||
| 651 | N-linked (GlcNAc...) asparagine | |||
| 698 | N-linked (GlcNAc...) asparagine | |||
| 769 | N-linked (GlcNAc...) asparagine |
|
||
| 782 | N-linked (GlcNAc...) asparagine | |||
| 786 |
|
|||
| 790 |
|
|||
| 791 |
|
|||
| 920 | N-linked (GlcNAc...) asparagine |
G05724UK
G31852PQ
G96577RX
G80075MS
G57776ZS
G16125XL
G80479JV
G85282JO
G20528HD
G87123QX
G79666IR
G07246CJ
G20706XG
G43223CG
G49906RN
G15664MX
G04657PL
G27058EU
G41071NU
G93718GY
G87661QW
G07755XJ
G72747WU
G54010QB
G50303LH
G58001LT
G43417UB
G29068FM
G23984SE
G70223PD
G59626AS
G01650EU
G23294PN
G80920RR
G37399XV
G62765YT
G47644PP
G28541PG
G95865ZB
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| IRS activation | Homo sapiens |
| Insulin receptor recycling | Homo sapiens |
| Insulin receptor signalling cascade | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| Signal attenuation | Homo sapiens |
| Signaling by Insulin receptor | Homo sapiens |
