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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Low affinity immunoglobulin epsilon Fc receptor
Summary
- UniProt ID
- P06734
- Gene Symbol
-
- FCER2
- CD23A
- CLEC4J
- FCE2
- IGEBF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- IgE-binding protein
- Lectin
- Metal-binding
- Palmitate
- Proteoglycan
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| extracellular exosome |
| external side of plasma membrane |
| GO Term |
|---|
| metal ion binding |
| carbohydrate binding |
| low-affinity IgE receptor activity |
| IgE binding |
| integrin binding |
Sequence
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS
Glycosylation Sites
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| NOTCH2 intracellular domain regulates transcription | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050597 | intestinal schistosomiasis | |
| DOID:0050746 | mantle cell lymphoma | |
| DOID:0050747 | obsolete lymphoplasmacytic lymphoma | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0050873 | follicular lymphoma | |
| DOID:0050909 | extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | |
| DOID:0060022 | CD40 ligand deficiency | |
| DOID:0060023 | immunodeficiency with hyper IgM type 3 | |
| DOID:0060058 | lymphoma |
