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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Proto-oncogene tyrosine-protein kinase receptor Ret
Summary
- UniProt ID
- P07949
- Gene Symbol
-
- RET
- CDHF12
- CDHR16
- PTC
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P07949
- PubChem
- P07949
- The Human Metabolome Database
- HMDBP01526
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell adhesion
- Cell membrane
- Chromosomal rearrangement
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Hirschsprung disease
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| dendrite |
| neuronal cell body |
| receptor complex |
| endosome membrane |
| early endosome |
| plasma membrane |
| axon |
| plasma membrane protein complex |
| GO Term |
|---|
| protein tyrosine kinase activity |
| transmembrane receptor protein tyrosine kinase activity |
| calcium ion binding |
| signaling receptor activity |
| ATP binding |
Sequence
MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWMLSPSAAKLMDTFDS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 98 | N-linked (GlcNAc...) asparagine |
|
||
| 151 | N-linked (GlcNAc...) asparagine |
|
||
| 179 |
|
|
||
| 199 | N-linked (GlcNAc...) asparagine |
|
||
| 336 | N-linked (GlcNAc...) asparagine |
|
||
| 343 | N-linked (GlcNAc...) asparagine | |||
| 361 | N-linked (GlcNAc...) asparagine |
|
||
| 367 | N-linked (GlcNAc...) asparagine |
|
||
| 377 | N-linked (GlcNAc...) asparagine |
|
||
| 394 | N-linked (GlcNAc...) asparagine |
|
G78959FJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Formation of the nephric duct | Homo sapiens |
| Formation of the ureteric bud | Homo sapiens |
| NPAS4 regulates expression of target genes | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| RET signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
