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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
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MIRAGE
Hepatocyte growth factor receptor
Summary
- UniProt ID
- P08581
- Gene Symbol
-
- MET
- Gene ID
- 4233
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011442
- GlyConnect
- GlyGen
- P08581
- PubChem
- P08581
- The Human Metabolome Database
- HMDBP09447
- The O-GlcNAc Database
- P08581
- RaftProt
- P08581
- O-GlcNAcAtlas
- P08581
- Re-Glyco
- P08581
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Chromosomal rearrangement
- Disease variant
- Disulfide bond
- Glycoprotein
- Non-syndromic deafness
- Phosphoprotein
- Proto-oncogene
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| membrane |
| receptor complex |
| postsynapse |
| basal plasma membrane |
| cell surface |
Sequence
MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 45 | N-linked (GlcNAc...) asparagine |
|
||
| 106 | N-linked (GlcNAc...) asparagine | |||
| 149 | N-linked (GlcNAc...) asparagine | |||
| 199 |
|
|
||
| 202 | N-linked (GlcNAc...) asparagine | |||
| 393 |
|
|
||
| 399 | N-linked (GlcNAc...) asparagine |
|
||
| 405 | N-linked (GlcNAc...) asparagine | |||
| 582 | O-linked (Man) threonine |
|
||
| 607 | N-linked (GlcNAc...) asparagine |
G50856PC
G56518TU
G93656SY
G80479JV
G07246CJ
G43223CG
G06356OH
G80920RR
G62765YT
G65184UU
G81637OR
G39471UU
G55132BD
G35541EV
G93718GY
G13131HA
G80075MS
G16125XL
G29545VG
G68490OW
G60834IK
G86880BF
G90382BL
G85282JO
G87123QX
G79666IR
G34989PA
G45395BF
G10819WX
G14972EH
G58954YZ
G37412TK
G08918WF
G61256FT
G70441OD
G87661QW
G83646BJ
G76295SF
G27058EU
G83460ZZ
G41071NU
G92406TI
G31916IQ
G45504EY
G82443XX
G37995HC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| Drug-mediated inhibition of MET activation | Homo sapiens |
| InlB-mediated entry of Listeria monocytogenes into host cell | Homo sapiens |
| MECP2 regulates neuronal receptors and channels | Homo sapiens |
| MET Receptor Activation | Homo sapiens |
| MET activates PI3K/AKT signaling | Homo sapiens |
| MET activates PTK2 signaling | Homo sapiens |
| MET activates PTPN11 | Homo sapiens |
| MET activates RAP1 and RAC1 | Homo sapiens |
| MET activates RAS signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050646 | distal arthrogryposis | |
| DOID:0110539 | autosomal recessive nonsyndromic deafness 97 | |
| DOID:12849 | autistic disorder | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4465 | papillary renal cell carcinoma | |
| DOID:4552 | large cell carcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9538 | multiple myeloma |
