Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Guidelines
MIRAGE
MET activates RAS signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HGF:p-4Y-MET dimerHGF:p-4Y-MET dimer:GRB2-1:SOS1GRB2-1:SOS1GTPp21 RAS:GTPGDPp21 RAS:GDPHGF:p-4Y MET dimer:MUC20MUC20HGF:p-4Y-MET dimer:RANBP9:SOS1SOS1RANBP9RANBP10HGF:p-4Y-MET dimer:RANBP10HGF:p-4Y-MET dimer:SHC1-2SHC1HGF:p-4Y-MET dimer:p-Y317-SHC1-2ATPADPHGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 8 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01111 GTPase NRas
  • HRAS1
  • NRAS
 view
P01112 GTPase HRas
  • HRAS
  • HRAS1
 view
P08581 Hepatocyte growth factor receptor
  • MET
 view
P14210 Hepatocyte growth factor
  • HGF
  • HPTA
 view
Q07889 Son of sevenless homolog 1
  • SOS1
 view
Q6VN20 Ran-binding protein 10
  • KIAA1464
  • RANBP10
 view
Q8N307 Mucin-20
  • KIAA1359
  • MUC20
 view
Q96S59 Ran-binding protein 9
  • RANBP9
  • RANBPM
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
About Release Notes Help Feedback
International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.2.1

Last updated: April 7, 2025