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Tyrosine-protein kinase HCK
Summary
- UniProt ID
- P08631
- Gene Symbol
-
- HCK
- Gene ID
- 3055
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative initiation
- Alternative splicing
- Cell junction
- Cell membrane
- Cell projection
- Cytoplasmic vesicle
- Cytoskeleton
- Exocytosis
- Golgi apparatus
- Host-virus interaction
- Inflammatory response
- Innate immunity
- Lysosome
- Myristate
- Nucleus
- Palmitate
- Phagocytosis
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| lysosome |
| cytoskeleton |
| plasma membrane |
| cell projection |
| intracellular membrane-bounded organelle |
| Golgi apparatus |
| cytosol |
| caveola |
| focal adhesion |
Sequence
MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIKPGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 347 |
|
|||
| 351 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FCGR activation | Homo sapiens |
| FCGR3A-mediated IL10 synthesis | Homo sapiens |
| FCGR3A-mediated phagocytosis | Homo sapiens |
| FLT3 signaling through SRC family kinases | Homo sapiens |
| Inactivation of CSF3 (G-CSF) signaling | Homo sapiens |
| Nef and signal transduction | Homo sapiens |
| Regulation of signaling by CBL | Homo sapiens |
| Signaling by CSF1 (M-CSF) in myeloid cells | Homo sapiens |
| Signaling by CSF3 (G-CSF) | Homo sapiens |
