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Alpha-2A adrenergic receptor

Summary

UniProt ID

P08913

Gene Symbol

ADRA2A
ADRA2R
ADRAR

Organism

Homo sapiens (human)

External Links

GlyGen: P08913
PubChem: P08913
The Human Metabolome Database: HMDBP01601

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 42 in total

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GO Term
adenylate cyclase-activating G protein-coupled receptor signaling pathway
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Ras protein signal transduction
Rho protein signal transduction
cellular response to hormone stimulus
vasodilation
positive regulation of potassium ion transport
positive regulation of MAPK cascade
regulation of vasoconstriction
actin cytoskeleton organization

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GO Term
basolateral plasma membrane
cytoplasm
plasma membrane
neuronal cell body
receptor complex
axon terminus
dopaminergic synapse
postsynaptic density membrane
glutamatergic synapse
presynaptic active zone membrane

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GO Term
alpha2-adrenergic receptor activity
alpha-1B adrenergic receptor binding
alpha-2C adrenergic receptor binding
thioesterase binding
heterotrimeric G-protein binding
epinephrine binding
norepinephrine binding
guanyl-nucleotide exchange factor activity
protein kinase binding
protein homodimerization activity

Annotation information from UniProt.

Sequence

MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
25	N-linked (GlcNAc...) asparagine			UniProt GlyGen
29	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Adrenaline signalling through Alpha-2 adrenergic receptor	Homo sapiens
Adrenaline,noradrenaline inhibits insulin secretion	Homo sapiens
Adrenoceptors	Homo sapiens
G alpha (i) signalling events	Homo sapiens
G alpha (z) signalling events	Homo sapiens
Surfactant metabolism	Homo sapiens