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Alkaline phosphatase, tissue-nonspecific isozyme

Summary

UniProt ID

P09242

Gene Symbol

Alpl
Akp-2
Akp2

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003320

GlyConnect

2116

GlyGen

P09242

PubChem

P09242

RaftProt

P09242

Annotation

Keyword

Biomineralization
Calcium
Cell membrane
Disulfide bond
GPI-anchor
Hydrolase
Magnesium
Metal-binding
Mitochondrion
Phosphoprotein
Reference proteome
Signal
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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GO Term
endochondral ossification
developmental process involved in reproduction
cellular homeostasis
bone mineralization
calcium ion homeostasis
response to vitamin B6
response to macrophage colony-stimulating factor
pyridoxal phosphate metabolic process
positive regulation of cold-induced thermogenesis
futile creatine cycle

Displaying **all 7** entries
GO Term
side of membrane
extracellular space
plasma membrane
extracellular matrix
mitochondrial membrane
extracellular membrane-bounded organelle
mitochondrial intermembrane space

Displaying **all 9** entries
GO Term
calcium ion binding
alkaline phosphatase activity
ATP hydrolysis activity
inorganic diphosphate phosphatase activity
pyrophosphatase activity
pyridoxal phosphatase activity
ADP phosphatase activity
phosphoamidase activity
phosphoethanolamine phosphatase activity

Annotation information from UniProt.

Sequence

MISPFLVLAIGTCLTNSFVPEKERDPSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNLKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGKAGAMTSQKDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWAGSGSAPSPGALLLPLAVLSLRTLF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
140	N-linked (GlcNAc...) asparagine	19349973	G80920RR	GlycoProtDB UniProt GlyGen
230	N-linked (GlcNAc...) asparagine	19349973	G82347DR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
271	N-linked (GlcNAc...) asparagine		G02815KT G06110VR	UniProt GlyGen GlyConnect
303	N-linked (GlcNAc...) asparagine	19349973	G37692EO	UniProt GlyGen
430	N-linked (GlcNAc...) asparagine	19349973	G62765YT G17013IQ G20861AN G39448FX G61514UE G74132QK G77994OH	GlycoProtDB UniProt GlyGen