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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement C1s subcomponent
Summary
- UniProt ID
- P09871
- Gene Symbol
-
- C1S
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011462
- GlyConnect
- GlyGen
- P09871
- PubChem
- P09871
- The Human Metabolome Database
- HMDBP07481
- The O-GlcNAc Database
- P09871
- RaftProt
- P09871
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Complement pathway
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Ehlers-Danlos syndrome
- Glycoprotein
- Hydroxylation
- Metal-binding
- Reference proteome
- Repeat
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| complement activation, classical pathway |
| proteolysis |
| innate immune response |
| GO Term |
|---|
| blood microparticle |
| extracellular region |
| extracellular space |
| GO Term |
|---|
| calcium ion binding |
| identical protein binding |
| serine-type endopeptidase activity |
Sequence
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 174 | N-linked (GlcNAc...) asparagine | |||
| 406 | N-linked (GlcNAc...) asparagine | |||
|
|
G00912UN
G48414YA
G84452RH
G59626AS
G94917XT
G47737VJ
G75983OB
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Classical antibody-mediated complement activation | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Regulation of Complement cascade | Homo sapiens |
