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MIRAGE
Keratin, type I cytoskeletal 10
Summary
- UniProt ID
- P13645
- Gene Symbol
-
- KPP
- KRT10
- Gene ID
- 3858
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Coiled coil
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Ichthyosis
- Intermediate filament
- Keratin
- Phosphoprotein
- Reference proteome
- Secreted
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| nucleus |
| cytoplasm |
| intermediate filament |
| membrane |
| keratin filament |
| cytosol |
| cell surface |
| extracellular exosome |
| cornified envelope |
| GO Term |
|---|
| protein heterodimerization activity |
| structural constituent of skin epidermis |
Sequence
MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGIFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 42 |
|
|||
| 48 |
|
|||
| 49 |
|
|||
| 56 |
|
|||
| 58 |
|
G57321FI
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Keratinization | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081359 | epidermolytic hyperkeratosis 2 | |
| DOID:4603 | epidermolytic hyperkeratosis |
