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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Aldo-keto reductase family 1 member A1
Summary
- UniProt ID
- P14550
- Gene Symbol
-
- AKR1A1
- ALDR1
- ALR
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P14550
- PubChem
- P14550
- The Human Metabolome Database
- HMDBP00507
- The O-GlcNAc Database
- P14550
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cell membrane
- Cytoplasm
- Direct protein sequencing
- Lipid metabolism
- NADP
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| synapse |
| extracellular exosome |
| apical plasma membrane |
| cytosol |
Sequence
MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Formation of xylulose-5-phosphate | Homo sapiens |
| Glutathione conjugation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050535 | exudative vitreoretinopathy | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:0050817 | Stargardt disease | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060058 | lymphoma | |
| DOID:0060060 | non-Hodgkin lymphoma | |
| DOID:0060119 | pharynx cancer | |
| DOID:0060224 | atrial fibrillation |
