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N-acetylglucosamine-6-sulfatase

Summary

UniProt ID

P15586

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011554

GlyConnect

GlyGen

P15586

PubChem

P15586

The Human Metabolome Database

HMDBP01597

The O-GlcNAc Database

P15586

O-GlcNAcAtlas

P15586

Annotation

Keyword

Alternative splicing
Calcium
Direct protein sequencing
Disease variant
Glycoprotein
Hydrolase
Lysosome
Metal-binding
Mucopolysaccharidosis
Phosphoprotein
Reference proteome
Signal

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
glycosaminoglycan catabolic process
keratan sulfate catabolic process

Displaying **all 5** entries
GO Term
extracellular region
extracellular exosome
azurophil granule lumen
lysosomal lumen
ficolin-1-rich granule lumen

Displaying **all 5** entries
GO Term
glycosaminoglycan binding
metal ion binding
sulfate binding
sulfuric ester hydrolase activity
N-acetylglucosamine-6-sulfatase activity

Annotation information from UniProt.

Sequence

MRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 21 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
48				GlyGen
106				GlyGen
111	N-linked (GlcNAc...) asparagine		G26377UA G01521EA G53075ES G12745LE G20577LS G11101UV G76915KR G07810QS G99679NM G63136LV G05962QB G49755GI G63980BQ G04854VP G94470IW G20706XG G00912UN G15664MX G85582CB G46503DX G80920RR G90659AW G77547TA G62765YT G28541PG G31852PQ G90575OW G41247ZX G50282JC G53641QT	GlycoProtDB UniProt GlyGen GlyConnect
112				GlyGen
117	N-linked (GlcNAc...) asparagine		G20991XV	GlycoProtDB UniProt GlyGen
178				GlyGen
183	N-linked (GlcNAc...) asparagine	12754519 19159218	G45395BF G07246CJ G43223CG G00912UN G87661QW G27058EU G83460ZZ G41071NU G86182NS G59626AS G80920RR G65184UU G42124LM G62765YT G11870QZ G47644PP G72790NZ G95177YH G05049YU G85269DF G95865ZB G31852PQ G49955PK G23719VF G11314AS G39188ZX G41247ZX G35029YA G57776ZU G36379GD G02815KT G84349RE G57317CE G92050GC G74724QE G92275SC G14669DU G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
198	N-linked (GlcNAc...) asparagine		G81124ET G70888PK G80479JV G04854VP G94470IW G43669FQ G07246CJ G56307ZW G87389XI G36442WJ G49018RC G72747WU G02886BB G10486CT G95865ZB G84349RE	GlycoProtDB UniProt GlyGen
210	N-linked (GlcNAc...) asparagine		G45504EY	GlycoProtDB UniProt GlyGen
275			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Keratan sulfate degradation	Homo sapiens
Lysosome Vesicle Biogenesis	Homo sapiens
MPS IIID - Sanfilippo syndrome D	Homo sapiens
Neutrophil degranulation	Homo sapiens

Human Protein Atlas

ENSG00000135677

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation