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Atrial natriuretic peptide receptor 1

Summary

UniProt ID

P16066

Gene Symbol

NPR1
ANPRA

Organism

Homo sapiens (human)

External Links

GlyGen: P16066
PubChem: P16066
The Human Metabolome Database: HMDBP01069

Annotation

Keyword

Chloride
Disulfide bond
GTP-binding
Glycoprotein
Lyase
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Vasoactive
cGMP biosynthesis

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

1

2

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GO Term
cell surface receptor signaling pathway
body fluid secretion
regulation of blood pressure
negative regulation of angiogenesis
negative regulation of cell growth
positive regulation of cGMP-mediated signaling
positive regulation of renal sodium excretion
blood vessel diameter maintenance
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway

Displaying **all 3** entries
GO Term
plasma membrane
receptor complex
ANPR-A receptor complex

Displaying **all 10** entries
GO Term
GTP binding
peptide receptor activity
adenylate cyclase activity
guanylate cyclase activity
protein kinase activity
ATP binding
G protein-coupled peptide receptor activity
peptide hormone binding
hormone binding
natriuretic peptide receptor activity

Annotation information from UniProt.

Sequence

MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	GlyTouCan ID	Source
34	N-linked (GlcNAc...) asparagine		UniProt GlyGen
45	N-linked (GlcNAc...) asparagine		UniProt GlyGen
212	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen
338	N-linked (GlcNAc...) asparagine		UniProt GlyGen
379	N-linked (GlcNAc...) asparagine		UniProt GlyGen
386	N-linked (GlcNAc...) asparagine		UniProt GlyGen
427	N-linked (GlcNAc...) asparagine	G80920RR G41247ZX	UniProt GlyGen
808		G83460ZZ	GlyGen