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Atrial natriuretic peptide receptor 1

Summary

UniProt ID

P16066

Gene Symbol

NPR1
ANPRA

Organism

Homo sapiens (human)

External Links

PubChem: P16066
The Human Metabolome Database: HMDBP01069

Annotation

Keyword

Chloride
Disulfide bond
GTP-binding
Glycoprotein
Lyase
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Vasoactive
cGMP biosynthesis

Gene Ontology (GO)

Displaying entries **11 - 15** of 15 in total

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1

2
GO Term
receptor guanylyl cyclase signaling pathway
positive regulation of cGMP-mediated signaling
cGMP-mediated signaling
positive regulation of urine volume
positive regulation of renal sodium excretion

Displaying **all 3** entries
GO Term
plasma membrane
receptor complex
ANPR-A receptor complex

Displaying **all 10** entries
GO Term
peptide receptor activity
protein kinase activity
G protein-coupled peptide receptor activity
hormone binding
peptide hormone binding
natriuretic peptide receptor activity
adenylate cyclase activity
guanylate cyclase activity
ATP binding
GTP binding

Annotation information from UniProt.

Sequence

MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
34	N-linked (GlcNAc...) asparagine	UniProt
45	N-linked (GlcNAc...) asparagine	UniProt
212	N-linked (GlcNAc...) asparagine	UniProt
338	N-linked (GlcNAc...) asparagine	UniProt
379	N-linked (GlcNAc...) asparagine	UniProt
386	N-linked (GlcNAc...) asparagine	UniProt
427	N-linked (GlcNAc...) asparagine	UniProt