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Guidelines
MIRAGE
Insulin-like growth factor-binding protein 3

Summary
UniProt ID
P17936
Gene Symbol
  • IBP3
  • IGFBP3
Gene ID
3486
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011577
GlyConnect
GlyGen
P17936
PubChem
P17936
Re-Glyco
P17936
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Apoptosis
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Growth factor binding
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 6 entries
GO Term
extracellular region
extracellular space
nucleus
endoplasmic reticulum lumen
insulin-like growth factor ternary complex
insulin-like growth factor binding protein complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 17 in total
Position Description PubMed ID GlyTouCan ID Source
116 N-linked (GlcNAc...) (complex) asparagine
136 N-linked (GlcNAc...) (complex) asparagine
145
148
151
153
155
156
157
161
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Post-translational protein phosphorylation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
TP53 Regulates Transcription of Death Receptors and Ligands Homo sapiens
Disease
Displaying all 8 entries
DO ID Disease Name Source
DOID:0050589 inflammatory bowel disease
DOID:10283 prostate cancer
DOID:10652 Alzheimer's disease
DOID:1612 breast cancer
DOID:2671 transitional cell carcinoma
DOID:3491 Turner syndrome
DOID:9352 type 2 diabetes mellitus
DOID:9744 type 1 diabetes mellitus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025