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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Prothrombin
Summary
- UniProt ID
- P19221
- Gene Symbol
-
- F2
- Cf2
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003459
- GlyGen
- P19221
- PubChem
- P19221
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- Gamma-carboxyglutamic acid
- Glycoprotein
- Kringle
- Reference proteome
- Repeat
- Serine protease
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| extracellular space |
| collagen-containing extracellular matrix |
Sequence
MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKRWIQKVIDQFG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 122 | N-linked (GlcNAc...) asparagine |
|
||
| 144 |
|
|||
| 413 | N-linked (GlcNAc...) asparagine | |||
| 553 | N-linked (GlcNAc...) asparagine |
G24748EV
G31986NC
G79652WX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Mus musculus |
| Common Pathway of Fibrin Clot Formation | Mus musculus |
| G alpha (q) signalling events | Mus musculus |
| Gamma-carboxylation of protein precursors | Mus musculus |
| Intrinsic Pathway of Fibrin Clot Formation | Mus musculus |
| Peptide ligand-binding receptors | Mus musculus |
| Platelet Aggregation (Plug Formation) | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Mus musculus |
| Thrombin signalling through proteinase activated receptors (PARs) | Mus musculus |
