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MIRAGE
Common Pathway of Fibrin Clot Formation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
factor Xafactor Xa:Factor Xa inhibitorsFactor Xa inhibitorsF2activated thrombin (factor IIa)F2O88783factor VaO88783FVa:FXafactor XaVa:Xa:Factor Xa inhibitorsFibrinogenfibrin monomerFgbE9PV24fibrin multimerfactor XIIIQ8BH61factor XIII cleaved tetramerCa2+F13bfactor XIIIaNH4+fibrin multimer, crosslinkedP32261SERPINC1:SERPINC1 activatorsSERPINC1 activatorsthrombin:SERPINC1:SERPINC1 activatorsthrombin:cleaved SERPINC1:SERPINC1 activatorsthrombin:cleaved SERPINC1Thbdactivated thrombin:thrombomodulinProtein CPROCR:Protein CProcrProcPROCR:Activated protein CActivated protein CPros1Activated protein C:Protein SO88783factor Vi intermediate formO88783factor Vifactor VIIIaInactivated factor VIIIF8F8P49182activated thrombin (factor IIa):SERPIND1activated thrombin (factor IIa)SERPINE2:GAG:activated thrombin (factor IIa)SERPINE2:GAGP70458SERPINA5:Activated protein CF2rPROCR:Activated protein C:F2RPROCR(18-?):Activated protein CProcrPRTN3:CD177PROCR(18-?):PRTN3:CD177
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025