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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neutrophil collagenase
Summary
- UniProt ID
- P22894
- Gene Symbol
-
- MMP8
- CLG1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P22894
- PubChem
- P22894
- The Human Metabolome Database
- HMDBP07814
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Collagen degradation
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| collagen-containing extracellular matrix |
| specific granule lumen |
| tertiary granule lumen |
| GO Term |
|---|
| serine-type endopeptidase activity |
| zinc ion binding |
| tumor necrosis factor binding |
| endopeptidase activity |
| metalloendopeptidase activity |
| peptidase activity |
Sequence
MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 54 | N-linked (GlcNAc...) asparagine | |||
| 73 | N-linked (GlcNAc...) asparagine |
|
||
| 112 |
|
|
||
| 204 | N-linked (GlcNAc...) asparagine |
|
||
| 246 | N-linked (GlcNAc...) asparagine |
|
G80075MS
G08918WF
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Homo sapiens |
| Collagen degradation | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
