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Collagenase 3 (Fragment)

Summary

UniProt ID

P23097

Gene Symbol

Mmp13

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P23097
Re-Glyco: P23097

Annotation

Keyword

Calcium
Collagen degradation
Direct protein sequencing
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Repeat
Signal
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular region
extracellular space
extracellular matrix
intercellular canaliculus

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 23 in total

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GO Term
growth plate cartilage development
positive regulation of pancreatic trypsinogen secretion
osteoblast differentiation
heart development
response to xenobiotic stimulus
response to hormone
extracellular matrix disassembly
collagen catabolic process
response to estrogen
estrous cycle

Displaying **all 10** entries
GO Term
fibronectin binding
serine-type endopeptidase activity
calcium ion binding
zinc ion binding
endopeptidase activity
metalloendopeptidase activity
collagen binding
peptidase activity
low-density lipoprotein particle receptor binding
calcium-dependent protein binding

Annotation information from UniProt.

Sequence

ATFFLLSWTHCWSLPLPYGDDDDDDLSEEDLEFAEHYLKSYYHPVTLAGILKKSTVTSTVDRLREMQSFFGLDVTGKLDDPTLDIMRKPRCGVPDVGVYNVFPRTLKWSQTNLTYRIVNYTPDISHSEVEKAFRKAFKVWSDVTPLNFTRIHDGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNLGGDAHFDDDETWTSSSKGYNLFIVAAHELGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPEKCDPALSLDAITSLRGETMIFKDRFFWRLHPQQVEPELFLTKSFWPELPNHVDAAYEHPSRDLMFIFRGRKFWALNGYDIMEGYPRKISDLGFPKEVKRLSAAVHFEDTGKTLFFSGNHVWSYDDANQTMDKDYPRLIEEEFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPTNSLLWC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
112	N-linked (GlcNAc...) asparagine	UniProt
147	N-linked (GlcNAc...) asparagine	UniProt
404	N-linked (GlcNAc...) asparagine	UniProt

Feature

Domains & sites

PTM

ProtVista

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Activation of Matrix Metalloproteinases	Rattus norvegicus
Assembly of collagen fibrils and other multimeric structures	Rattus norvegicus
Collagen degradation	Rattus norvegicus
Degradation of the extracellular matrix	Rattus norvegicus

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:2316	brain ischemia	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:90	degenerative disc disease	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements