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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
degenerative disc disease
Summary
- Synonym
-
- cervical disc degenerative disease
- intervertebral disc degeneration
- lumbar disc degeneration
- vertebral disc disease
- Definition
- A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.
- Super Class
- bone deterioration disease
External Links
- Disease Ontology
- DOID:90
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 176 | ACAN | aggrecan | |
| 1277 | COL1A1 | collagen type I alpha 1 chain | |
| 1280 | COL2A1 | collagen type II alpha 1 chain | |
| 1300 | COL10A1 | collagen type X alpha 1 chain | |
| 1398 | CRK | CRK proto-oncogene, adaptor protein | |
| 2353 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit | |
| 2932 | GSK3B | glycogen synthase kinase 3 beta | |
| 4312 | MMP1 | matrix metallopeptidase 1 | |
| 4314 | MMP3 | matrix metallopeptidase 3 | |
| 4322 | MMP13 | matrix metallopeptidase 13 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11595 | Acan | aggrecan | |
| 12824 | Col2a1 | collagen, type II, alpha 1 | |
| 12842 | Col1a1 | collagen, type I, alpha 1 | |
| 14281 | Fos | FBJ osteosarcoma oncogene | |
| 17386 | Mmp13 | matrix metallopeptidase 13 | |
| 18049 | Ngf | nerve growth factor | |
| 18053 | Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | |
| 18491 | Pappa | pregnancy-associated plasma protein A | |
| 21857 | Timp1 | tissue inhibitor of metalloproteinase 1 | |
| 23794 | Adamts5 | ADAM metallopeptidase with thrombospondin type 1 motif 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24596 | Ngfr | nerve growth factor receptor | |
| 25412 | Col2a1 | collagen type II alpha 1 chain | |
| 29393 | Col1a1 | collagen type I alpha 1 chain | |
| 58968 | Acan | aggrecan | |
| 66015 | Adamts4 | ADAM metallopeptidase with thrombospondin type 1 motif, 4 | |
| 84027 | Gsk3b | glycogen synthase kinase 3 beta | |
| 116510 | Timp1 | TIMP metallopeptidase inhibitor 1 | |
| 304135 | Adamts5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | |
| 310738 | Ngf | nerve growth factor |
