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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Diacylglycerol kinase alpha
Summary
- UniProt ID
- P23743
- Gene Symbol
-
- DGKA
- DAGK
- DAGK1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P23743
- PubChem
- P23743
- SwissLipids
- The Human Metabolome Database
- HMDBP00233
- The O-GlcNAc Database
- P23743
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Calcium
- Cytoplasm
- Kinase
- Lipid metabolism
- Reference proteome
- Repeat
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| membrane |
| plasma membrane |
| GO Term |
|---|
| calcium ion binding |
| ATP-dependent diacylglycerol kinase activity |
| phospholipid binding |
| ATP binding |
| lipid binding |
| kinase activity |
| alkylglycerol kinase activity |
Sequence
MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRSTNFFGFLS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Effects of PIP2 hydrolysis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11847 | coronary thrombosis | |
| DOID:1240 | leukemia | |
| DOID:1324 | lung cancer | |
| DOID:1380 | endometrial cancer | |
| DOID:1474 | aggressive periodontitis | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1749 | squamous cell carcinoma |
