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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
DNA-directed RNA polymerase II subunit RPB1
Summary
- UniProt ID
- P24928
- Gene Symbol
-
- POLR2A
- POLR2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P24928
- PubChem
- P24928
- The Human Metabolome Database
- HMDBP00739
- The O-GlcNAc Database
- P24928
- O-GlcNAcAtlas
- P24928
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Chromosome
- Cytoplasm
- DNA-binding
- DNA-directed RNA polymerase
- Disease variant
- Host-virus interaction
- Hydrolase
- Intellectual disability
- Isopeptide bond
- Magnesium
- Metal-binding
- Methylation
- Nucleus
- Phosphoprotein
- RNA-directed RNA polymerase
- Reference proteome
- Repeat
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| chromosome |
| cytoplasm |
| nucleoplasm |
| RNA polymerase II, core complex |
| GO Term |
|---|
| DNA binding |
| RNA binding |
| hydrolase activity |
| zinc ion binding |
| kinase binding |
| microfibril binding |
| promoter-specific chromatin binding |
| ubiquitin protein ligase binding |
| magnesium ion binding |
| RNA polymerase II activity |
Sequence
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 1116 |
|
|||
| 1534 |
|
|||
| 1619 |
|
|||
| 1621 |
|
|||
| 1822 |
|
|||
| 1847 |
|
|||
| 1889 |
|
|||
| 1892 |
|
|||
| 1894 |
|
|||
| 1898 |
|
G41247ZX
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Signaling by FGFR2 IIIa TM | Homo sapiens |
| TP53 Regulates Transcription of DNA Repair Genes | Homo sapiens |
| Tat-mediated HIV elongation arrest and recovery | Homo sapiens |
| Tat-mediated elongation of the HIV-1 transcript | Homo sapiens |
| Transcription of the HIV genome | Homo sapiens |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | Homo sapiens |
| Transcriptional regulation by small RNAs | Homo sapiens |
| U12 Dependent Splicing | Homo sapiens |
| Viral Messenger RNA Synthesis | Homo sapiens |
| mRNA Capping | Homo sapiens |
