TP53 Regulates Transcription of DNA Repair Genes

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-S15,S20-TP53 TetramerAP-1:p-S15,S20-TP53 Tetramer:MSH2 GeneAP-1MSH2 GeneMSH2PMS2 Genep-S15,S20-TP53 Tetramer:PMS2 GenePMS2p-S15,S20-TP53 Tetramer:MLH1 GeneMLH1 GeneMLH1FANCC Genep-S15,S20-TP53 Tetramer:FANCC GeneFANCCp-S15,S20-TP53 Tetramer:DDB2 GeneDDB2 GeneDDB2CCNK Genep-S15,S20-TP53 Tetramer:CCNK GeneCCNKCRK7CCNK:CDK12CHEDCCNK:CDK13CCNK:CDK12:Elongation Complex at DNA Repair GenesElongation Complex at DNA Repair GenesATPCCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genesADPDNA repair genes regulated by CDK12BRCA1, ATR, FANCD2, FANCI, ATM, MDC1, CHEK1, RAD51D
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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