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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tumor necrosis factor receptor superfamily member 6
Summary
- UniProt ID
- P25445
- Gene Symbol
-
- FAS
- APT1
- FAS1
- TNFRSF6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Calmodulin-binding
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| tumor necrosis factor receptor activity |
| calmodulin binding |
| signaling receptor activity |
| kinase binding |
| identical protein binding |
Sequence
MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 28 | O-linked (GalNAc...) threonine | |||
| 38 |
|
|||
| 39 |
|
|||
| 40 |
|
|||
| 42 |
|
|||
| 43 |
|
|||
| 46 |
|
|||
| 118 | N-linked (GlcNAc...) asparagine | |||
| 132 |
|
|
||
| 136 | N-linked (GlcNAc...) asparagine |
G29931IJ
G43417UB
G57321FI
G57317CE
G29068FM
G80075MS
G85282JO
G45395BF
G07246CJ
G14972EH
G43223CG
G08918WF
G70441OD
G87661QW
G83646BJ
G04657PL
G27058EU
G83460ZZ
G41071NU
G07755XJ
G86182NS
G70619PT
G59626AS
G08290VR
G42124LM
G90659AW
G62765YT
G95177YH
G05049YU
G23719VF
G37995HC
G83633GK
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Homo sapiens |
| Dimerization of procaspase-8 | Homo sapiens |
| FasL/ CD95L signaling | Homo sapiens |
| Ligand-dependent caspase activation | Homo sapiens |
| RIPK1-mediated regulated necrosis | Homo sapiens |
| Regulation by c-FLIP | Homo sapiens |
| TP53 Regulates Transcription of Death Receptors and Ligands | Homo sapiens |
