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Nuclear factor NF-kappa-B p105 subunit

Summary

UniProt ID

P25799

Gene Symbol

Nfkb1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P25799
PubChem: P25799
The O-GlcNAc Database: P25799
O-GlcNAcAtlas: P25799

Annotation

Keyword

3D-structure
ANK repeat
Acetylation
Activator
Alternative splicing
Apoptosis
Cytoplasm
DNA-binding
Direct protein sequencing
Hydroxylation
Isopeptide bond
Lipoprotein
Nucleus
Phosphoprotein
Reference proteome
Repeat
S-nitrosylation
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **21 - 30** of 46 in total

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GO Term
cellular response to lipopolysaccharide
positive regulation of transcription initiation by RNA polymerase II
negative regulation of transcription by RNA polymerase II
canonical NF-kappaB signal transduction
negative regulation of DNA-templated transcription
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
MAPK cascade
JNK cascade
non-canonical NF-kappaB signal transduction

Displaying **all 9** entries
GO Term
protein-containing complex
mitochondrion
cytosol
nucleoplasm
transcription regulator complex
NF-kappaB p50/p65 complex
chromatin
nucleus
cytoplasm

Displaying entries **1 - 10** of 17 in total

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GO Term
DNA binding
chromatin binding
protein-containing complex binding
heat shock protein binding
identical protein binding
actinin binding
transcription cis-regulatory region binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription repressor activity, RNA polymerase II-specific

Annotation information from UniProt.

Sequence

MADDDPYGTGQMFHLNTALTHSIFNAELYSPEIPLSTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLTDREKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGSTGSPGPGYGYSNYGFPPYGGITFHPGVTKSNAGVTHGTINTKFKNGPKDCAKSDDEESLTLPEKETEGEGPSLPMACTKTEPIALASTMEDKEQDMGFQDNLFLEKALQLARRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLHLAAKEGHDRILSILLKSRKAAPLIDHPNGEGLNAIHIAVMSNSLPCLLLLVAAGAEVNAQEQKSGRTALHLAVEYDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEKAGEDEGVVPGTTPLDMAANWQVFDILNGKPYEPVFTSDDILPQGDMKQLTEDTRLQLCKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELMEALQQMGYTEAIEVIQAAFRTPATTASSPVTTAQVHCLPLSSSSTRQHIDELRDSDSVCDSGVETSFRKLSFTESLTGDSPLLSLNKMPHGYGQEGPIEGKI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
890	G49108TO	GlyGen The O-GlcNAc Database
893	G49108TO	GlyGen
894	G49108TO	GlyGen
901	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Activation of NF-kappaB in B cells	Mus musculus
CD209 (DC-SIGN) signaling	Mus musculus
CLEC7A (Dectin-1) signaling	Mus musculus
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	Mus musculus
Downstream TCR signaling	Mus musculus
FCERI mediated NF-kB activation	Mus musculus
Interleukin-1 processing	Mus musculus
Interleukin-1 signaling	Mus musculus
MAP3K8 (TPL2)-dependent MAPK1/3 activation	Mus musculus
NF-kB is activated and signals survival	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements