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Tyrosine-protein kinase Lyn
Summary
- UniProt ID
- P25911
- Gene Symbol
-
- Lyn
- Gene ID
- 17096
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Cytoplasm
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Myristate
- Nucleus
- Palmitate
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| cytosol |
| adherens junction |
| perinuclear region of cytoplasm |
| cytoplasmic side of plasma membrane |
| mitochondrial crista |
| membrane raft |
| integrin alpha2-beta1 complex |
| glutamatergic synapse |
| nucleus |
Sequence
MGCIKSKRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 19 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CD209 (DC-SIGN) signaling | Mus musculus |
| CD22 mediated BCR regulation | Mus musculus |
| CD28 co-stimulation | Mus musculus |
| CTLA4 inhibitory signaling | Mus musculus |
| Cell surface interactions at the vascular wall | Mus musculus |
| Cyclin D associated events in G1 | Mus musculus |
| Dectin-2 family | Mus musculus |
| EPH-ephrin mediated repulsion of cells | Mus musculus |
| EPHA-mediated growth cone collapse | Mus musculus |
| EPHB-mediated forward signaling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9074 | systemic lupus erythematosus |
