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EPHB-mediated forward signaling

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-3928662

PubChem

R-MMU-3928662

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 25 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
A2CG49	Kalirin	Kalrn	view
O08644	Ephrin type-B receptor 6	Cekl Ephb6	view
O35393	Ephrin-B3	Efnb3 RP23-56I20.5-001	view
O88643	Serine/threonine-protein kinase PAK 1	Pak1 Paka	view
P05480	Proto-oncogene tyrosine-protein kinase Src	Src	view
P25911	Tyrosine-protein kinase Lyn	Lyn	view
P35438	Glutamate receptor ionotropic, NMDA 1	Glurz1 Grin1	view
P43407	Syndecan-2	Hspg1 Sdc2 Synd2	view
P52795	Ephrin-B1	Efnb1 Epl2 Eplg2 Lerk2 Stra1	view
P52800	Ephrin-B2	Efnb2 Elf2 Epl5 Eplg5 Htkl Lerk5	view

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