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MIRAGE
5-hydroxytryptamine receptor 2C

Summary
UniProt ID
P28335
Gene Symbol
  • HTR1C
  • HTR2C
Gene ID
3358
Organism
Homo sapiens (human)
PubChem
P28335
The Human Metabolome Database
HMDBP02700
Re-Glyco
P28335
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Behavior
  • Cell membrane
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • RNA editing
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 4 entries
GO Term
plasma membrane
dendrite
synapse
G protein-coupled serotonin receptor complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
39 N-linked (GlcNAc...) asparagine
204 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
G alpha (q) signalling events Homo sapiens
Serotonin receptors Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:3312 bipolar disorder
DOID:5419 schizophrenia
DOID:9970 obesity
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: March 31, 2025