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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Syndecan-2
Summary
- UniProt ID
- P34741
- Gene Symbol
-
- SDC2
- HSPG1
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P34741
- PubChem
- P34741
- The Human Metabolome Database
- HMDBP10737
Annotation
- Keyword
-
- 3D-structure
- Differentiation
- Heparan sulfate
- Neurogenesis
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell migration |
| dendrite morphogenesis |
| regulation of dendrite morphogenesis |
| GO Term |
|---|
| plasma membrane |
| collagen-containing extracellular matrix |
| endoplasmic reticulum lumen |
| Golgi lumen |
| cell surface |
| lysosomal lumen |
| GO Term |
|---|
| PDZ domain binding |
| identical protein binding |
Sequence
MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 41 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 55 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 57 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 74 |
|
|||
| 77 |
|
|||
| 80 |
|
|||
| 81 |
|
|||
| 86 |
|
|||
| 88 |
|
|||
| 89 |
|
G57321FI
G57317CE
G73004SD
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Homo sapiens |
| Attachment and Entry | Homo sapiens |
| Cell surface interactions at the vascular wall | Homo sapiens |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | Homo sapiens |
| Defective B3GAT3 causes JDSSDHD | Homo sapiens |
| Defective B4GALT7 causes EDS, progeroid type | Homo sapiens |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | Homo sapiens |
| Defective EXT2 causes exostoses 2 | Homo sapiens |
| EPHB-mediated forward signaling | Homo sapiens |
| HS-GAG biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060190 | ileocolitis | |
| DOID:0060255 | rippling muscle disease 2 | |
| DOID:0060270 | pontocerebellar hypoplasia type 2D | |
| DOID:0060276 | pontocerebellar hypoplasia type 7 | |
| DOID:0060277 | pontocerebellar hypoplasia type 8 | |
| DOID:0060278 | pontocerebellar hypoplasia type 9 | |
| DOID:0060469 | Miller-Dieker lissencephaly syndrome | |
| DOID:0060807 | syndromic X-linked intellectual disability Najm type | |
| DOID:0070027 | CST3-related cerebral amyloid angiopathy | |
| DOID:0070247 | autosomal dominant Emery-Dreifuss muscular dystrophy 2 |
