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Tyrosine-protein phosphatase non-receptor type 11

Summary

UniProt ID

P35235

Gene Symbol

Ptpn11

Organism

Mus musculus (house mouse)

External Links

GlyGen: P35235
PubChem: P35235

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Phosphoprotein
Protein phosphatase
Reference proteome
Repeat
SH2 domain

Gene Ontology (GO)

Displaying entries **11 - 20** of 53 in total

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GO Term
negative regulation of growth hormone secretion
DNA damage checkpoint signaling
microvillus organization
regulation of protein export from nucleus
genitalia development
Bergmann glial cell differentiation
cerebellar cortex formation
negative regulation of cortisol secretion
intestinal epithelial cell migration
triglyceride metabolic process

Displaying **all 5** entries
GO Term
cytosol
nucleus
cytoplasm
protein-containing complex
plasma membrane raft

Displaying entries **1 - 10** of 16 in total

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GO Term
phosphotyrosine residue binding
D1 dopamine receptor binding
peptide hormone receptor binding
protein tyrosine phosphatase activity
insulin receptor binding
protein kinase binding
protein domain specific binding
signaling receptor complex adaptor activity
receptor tyrosine kinase binding
phospholipase binding

Annotation information from UniProt.

Sequence

MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
217			G41840AI	GlyGen
566				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 37 in total

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Pathway Name	Organism
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Mus musculus
CTLA4 inhibitory signaling	Mus musculus
Costimulation by the CD28 family	Mus musculus
Downstream signal transduction	Mus musculus
FRS-mediated FGFR1 signaling	Mus musculus
FRS-mediated FGFR2 signaling	Mus musculus
FRS-mediated FGFR3 signaling	Mus musculus
FRS-mediated FGFR4 signaling	Mus musculus
GAB1 signalosome	Mus musculus
GPVI-mediated activation cascade	Mus musculus