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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine-protein phosphatase non-receptor type 11
Summary
- UniProt ID
- P35235
- Gene Symbol
-
- Ptpn11
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Repeat
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| lipid metabolic process |
| signal transduction |
| positive regulation of signal transduction |
| GO Term |
|---|
| cytosol |
| nucleus |
| cytoplasm |
| protein-containing complex |
| plasma membrane raft |
| GO Term |
|---|
| insulin receptor substrate binding |
| cadherin binding |
| cell adhesion molecule binding |
| protein tyrosine kinase binding |
| phosphoprotein phosphatase activity |
| non-membrane spanning protein tyrosine phosphatase activity |
Sequence
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR
Glycosylation Sites
G41840AI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-20 family signaling | Mus musculus |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | Mus musculus |
| Interleukin-6 signaling | Mus musculus |
| MAPK1 (ERK2) activation | Mus musculus |
| MAPK3 (ERK1) activation | Mus musculus |
| MET activates PTPN11 | Mus musculus |
| Negative regulation of FGFR1 signaling | Mus musculus |
| Negative regulation of FGFR2 signaling | Mus musculus |
| Negative regulation of FGFR3 signaling | Mus musculus |
| Negative regulation of FGFR4 signaling | Mus musculus |
