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MIRAGE
Tyrosine-protein kinase BTK
Summary
- UniProt ID
- P35991
- Gene Symbol
-
- Bpk
- Btk
- Gene ID
- 12229
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Adaptive immunity
- Apoptosis
- Cell membrane
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Innate immunity
- Lipid-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- SH2 domain
- SH3 domain
- Transcription regulation
- Tyrosine-protein kinase
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| membrane raft |
| nucleus |
| cytoplasm |
| plasma membrane |
| cytoplasmic vesicle |
| cytosol |
| perinuclear region of cytoplasm |
Sequence
MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVIPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKPLPPEPTAAPISTTELKKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEES
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | Mus musculus |
| DAP12 signaling | Mus musculus |
| FCERI mediated Ca+2 mobilization | Mus musculus |
| G alpha (12/13) signalling events | Mus musculus |
| G alpha (q) signalling events | Mus musculus |
| G beta:gamma signalling through BTK | Mus musculus |
| RHO GTPases Activate WASPs and WAVEs | Mus musculus |
| Regulation of actin dynamics for phagocytic cup formation | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14179 | X-linked agammaglobulinemia |
