Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
BCRAntigen:BCRAntigenAntigen:p-BCRAntigen:p-BCR:SYKSYKAntigen:p-BCR:p-SYKATPADPAntigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1BLNK:GRB2:SOS1:CIN85Plcg2Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2Vav1Nck1BtkPIP3BTK inhibitorsBTK:BTK inhibitorsp-CD19:VAV1CD19 SignalosomeGrb2PIK3CD:PIK3R1Dapp1p-Y139-DAPP1:PIP3p-Y139-DAPP1:PLCG2:PIP3PIP2IP3DAGSTIM1:CalciumSTIM1 DimerCa2+Trpc1STIM1:TRPC1Ca2+
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025