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DNA-binding protein SMUBP-2

Summary

UniProt ID: P38935
Gene Symbol: IGHMBP2 SMBP2 SMUBP2
Gene ID: 3508
Organism: Homo sapiens (human)

External Links

GlyGen: P38935
The Human Metabolome Database: HMDBP11959
Re-Glyco: P38935

Annotation

Keyword: 3D-structure Acetylation Activator Cell projection Charcot-Marie-Tooth disease Cytoplasm DNA-binding Direct protein sequencing Disease variant Helicase Neurodegeneration Nucleus Proteomics identification Reference proteome Ribonucleoprotein Transcription regulation Zinc-finger tRNA-binding

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
nucleus	IDA	PMID
nucleus	IBA	GO_REF
nucleus	IEA	GO_REF
nucleoplasm	IDA	GO_REF
cytoplasm	IDA	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

cellular anatomical structure [inference]

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nuclear body

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	Reference
tRNA binding	IDA	PMID
DNA binding	IDA	PMID
DNA binding	IEA	GO_REF GO_REF
DNA helicase activity	TAS	PMID
single-stranded DNA binding	TAS	PMID PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

nucleic acid conformation isomerase activity [inference]

helicase activity [inference]

DNA helicase activity

RNA helicase activity [inference]

5'-3' RNA helicase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity [inference]

DNA helicase activity

RNA helicase activity [inference]

5'-3' RNA helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

DNA helicase activity

catalytic activity, acting on RNA [inference]

RNA helicase activity [inference]

5'-3' RNA helicase activity

binding [inference]

nucleic acid binding [inference]

DNA binding

single-stranded DNA binding

RNA binding

protein binding [inference]

transcription factor binding [inference]

general transcription initiation factor binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity [inference]

DNA helicase activity

RNA helicase activity [inference]

5'-3' RNA helicase activity

ATP-dependent activity, acting on DNA

DNA helicase activity

ATP-dependent activity, acting on RNA

RNA helicase activity [inference]

5'-3' RNA helicase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
602				GlyGen
811				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110171	Charcot-Marie-Tooth disease axonal type 2S	Alliance of Genome Resources
DOID:0111064	autosomal recessive distal hereditary motor neuronopathy 1	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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