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Signal transducer and activator of transcription 3

Summary

UniProt ID

P42227

Gene Symbol

Stat3
Aprf

Organism

Mus musculus (house mouse)

External Links

GlyGen: P42227
PubChem: P42227
The O-GlcNAc Database: P42227
RaftProt: P42227
O-GlcNAcAtlas: P42227

Annotation

Keyword

3D-structure
Acetylation
Activator
Acute phase
Alternative splicing
Cytoplasm
DNA-binding
Direct protein sequencing
Nucleus
Phosphoprotein
Reference proteome
SH2 domain
Transcription regulation

Gene Ontology (GO)

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GO Term
eating behavior
positive regulation of erythrocyte differentiation
positive regulation of angiogenesis
negative regulation of glycolytic process
negative regulation of inflammatory response
modulation of chemical synaptic transmission
regulation of cell cycle
cellular response to cytokine stimulus
regulation of feeding behavior
negative regulation of inflammatory response to wounding

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GO Term
nucleoplasm
cytosol
chromatin
nucleus
cytoplasm
mitochondrial inner membrane
plasma membrane
protein-containing complex
transcription regulator complex
postsynaptic density

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GO Term
acetylation-dependent protein binding
protein kinase binding
protein phosphatase binding
chromatin DNA binding
signaling adaptor activity
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
protein dimerization activity
primary miRNA binding

Annotation information from UniProt.

Sequence

MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	GlyTouCan ID	Source
401	G97993TU	GlyGen
714	G49108TO	GlyGen The O-GlcNAc Database
716	G49108TO	GlyGen
717	G49108TO	GlyGen The O-GlcNAc Database
719	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Interleukin-6 signaling	Mus musculus
Interleukin-7 signaling	Mus musculus
Interleukin-9 signaling	Mus musculus
MET activates STAT3	Mus musculus
PKR-mediated signaling	Mus musculus
PTK6 Activates STAT3	Mus musculus
STAT3 nuclear events downstream of ALK signaling	Mus musculus
Signaling by ALK	Mus musculus
Signaling by SCF-KIT	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements