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Interleukin-12 receptor subunit beta-1

Summary

UniProt ID

P42701

Gene Symbol

IL12RB1
IL12R
IL12RB

Organism

Homo sapiens (human)

External Links

PubChem: P42701

Annotation

Keyword

3D-structure
Alternative splicing
Disease variant
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

1

2

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GO Term
positive regulation of T cell mediated cytotoxicity
positive regulation of T-helper 1 type immune response
signal transduction
cytokine-mediated signaling pathway
positive regulation of type II interferon production
positive regulation of memory T cell differentiation
positive regulation of T-helper 17 type immune response
cellular response to type II interferon
positive regulation of T-helper 17 cell lineage commitment
interleukin-12-mediated signaling pathway

Displaying **all 5** entries
GO Term
plasma membrane
receptor complex
external side of plasma membrane
interleukin-12 receptor complex
interleukin-23 receptor complex

Displaying **all 2** entries
GO Term
cytokine receptor activity
cytokine binding

Annotation information from UniProt.

Sequence

MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRYECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWARNQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSPWKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQVRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRTLHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHTEPVALNISVGTNGTTMYWPARAQSMTYCIEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKCYYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIEVQVSDWLIFFASLGSFLSILLVGVLGYLGLNRAARHLCPPLPTPCASSAIEFPGGKETWQWINPVDFQEEASLQEALVVEMSWDKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKAKM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
121	N-linked (GlcNAc...) asparagine	UniProt
329	N-linked (GlcNAc...) asparagine	UniProt
346	N-linked (GlcNAc...) asparagine	UniProt
352	N-linked (GlcNAc...) asparagine	UniProt
442	N-linked (GlcNAc...) asparagine	UniProt
456	N-linked (GlcNAc...) asparagine	UniProt