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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Integrin alpha-V
Summary
- UniProt ID
- P43406
- Gene Symbol
-
- Itgav
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003628
- GlyConnect
- GlyGen
- P43406
- PubChem
- P43406
Annotation
- Keyword
-
- Angiogenesis
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| focal adhesion assembly |
| positive regulation of small GTPase mediated signal transduction |
| trophoblast giant cell differentiation |
| response to nitric oxide |
| negative regulation of extrinsic apoptotic signaling pathway |
| GO Term |
|---|
| cytosol |
| external side of plasma membrane |
| cell surface |
| plasma membrane |
| membrane |
| integrin alphav-beta1 complex |
| integrin alphav-beta3 complex |
| integrin alphav-beta8 complex |
| alphav-beta3 integrin-HMGB1 complex |
| focal adhesion |
Sequence
MAAPGRLLLRPRPGGLLLLLPGLLLPLADAFNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSRMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAVGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQILEGQWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVYPSILNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPRKLHFQVELLLDKLKQKGAIRRALFLHNRSPVHSKTMTVFRGGQMQCEELVAYLRDESEFRDKLTPITIFMEYRLDQRTAADATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVNSDQKKIYIGDDNPLTLTVKAQNQGEGAYEAELIVSIPPQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNVSPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWEYKENPETEEDVGPIVQHIYELRNNGPSSFSKAILNLQWPYKYNNNTLLYILHYDIDGPMNCTADTEINPLRIKTPEKNDTAAAGQGERNHLITKRDLTLREGDVHTLGCGIAKCLQITCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKNLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 941 | N-linked (GlcNAc...) asparagine | |||
| 969 | N-linked (GlcNAc...) asparagine |
|
||
| 976 | N-linked (GlcNAc...) asparagine |
|
G70101JE
G62765YT
G64527OM
G05724UK
G39188ZX
G06110VR
G66538GV
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cross-presentation of particulate exogenous antigens (phagosomes) | Mus musculus |
| ECM proteoglycans | Mus musculus |
| Elastic fibre formation | Mus musculus |
| Integrin cell surface interactions | Mus musculus |
| Molecules associated with elastic fibres | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| PECAM1 interactions | Mus musculus |
| Signal transduction by L1 | Mus musculus |
| Syndecan interactions | Mus musculus |
| TGF-beta receptor signaling activates SMADs | Mus musculus |
