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MIRAGE
Natural resistance-associated macrophage protein 1

Summary
UniProt ID
P49279
Gene Symbol
  • LSH
  • NRAMP
  • NRAMP1
  • SLC11A1
Gene ID
6556
Organism
Homo sapiens (human)
PubChem
P49279
The Human Metabolome Database
HMDBP08680
Re-Glyco
P49279
Annotation
Keyword
  • Alternative splicing
  • Endosome
  • Glycoprotein
  • Iron transport
  • Lysosome
  • Proteomics identification
  • Reference proteome
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 9 entries
GO Term
lysosomal membrane
endosome membrane
late endosome membrane
ficolin-1-rich granule membrane
phagocytic vesicle membrane
tertiary granule membrane
lysosome
plasma membrane
late endosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLSEKIPIPDTKPGTFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRADIREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGVILGCLFGPAALYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAINLYFVVSYLPSLPHPAYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHSSHHHFLYGLLEEDQKGETSG
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
324 N-linked (GlcNAc...) asparagine
338 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Ion influx/efflux at host-pathogen interface Homo sapiens
Metal ion SLC transporters Homo sapiens
Neutrophil degranulation Homo sapiens
ROS and RNS production in phagocytes Homo sapiens
Disease
Displaying entries 1 - 10 of 19 in total
DO ID Disease Name Source
DOID:0050456 Buruli ulcer disease
DOID:0050589 inflammatory bowel disease
DOID:0060704 lymphoproliferative syndrome
DOID:1024 leprosy
DOID:11054 urinary bladder cancer
DOID:11335 sarcoidosis
DOID:13241 Behcet's disease
DOID:2377 multiple sclerosis
DOID:2957 pulmonary tuberculosis
DOID:399 tuberculosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025