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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fms-related tyrosine kinase 3 ligand
Summary
- UniProt ID
- P49771
- Gene Symbol
-
- FLT3LG
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P49771
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cytokine
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| embryonic hemopoiesis |
| signal transduction |
| positive regulation of cell population proliferation |
| GO Term |
|---|
| cytosol |
| cell surface |
| extracellular region |
| extracellular space |
| plasma membrane |
| membrane |
| GO Term |
|---|
| signaling receptor binding |
| cytokine activity |
| receptor tyrosine kinase binding |
Sequence
MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTAPQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPVPSPQDLLLVEH
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| FLT3 Signaling | Homo sapiens |
| FLT3 signaling by CBL mutants | Homo sapiens |
| FLT3 signaling through SRC family kinases | Homo sapiens |
| Negative regulation of FLT3 | Homo sapiens |
| PI3K Cascade | Homo sapiens |
| PI3K/AKT Signaling | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| STAT5 Activation | Homo sapiens |
