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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Chloride channel protein ClC-Kb
Summary
- UniProt ID
- P51801
- Gene Symbol
-
- CLCNKB
- Organism
- Homo sapiens (human)
External Links
- The Human Metabolome Database
- HMDBP08183
Annotation
- Keyword
-
- Alternative splicing
- Bartter syndrome
- CBS domain
- Calcium
- Cell membrane
- Chloride channel
- Deafness
- Disease variant
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Transmembrane helix
- Voltage-gated channel
- Gene Ontology (GO)
| GO Term |
|---|
| renal absorption |
| renal sodium ion absorption |
| transepithelial chloride transport |
| chloride transport |
| GO Term |
|---|
| plasma membrane |
| chloride channel complex |
| basolateral plasma membrane |
| GO Term |
|---|
| metal ion binding |
| chloride channel activity |
| voltage-gated chloride channel activity |
Sequence
MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTNPPAPK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 193 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Stimuli-sensing channels | Homo sapiens |
