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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
5'-AMP-activated protein kinase catalytic subunit alpha-2
Summary
- UniProt ID
- P54646
- Gene Symbol
-
- PRKAA2
- AMPK
- AMPK2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Autophagy
- Biological rhythms
- Cholesterol biosynthesis
- Chromatin regulator
- Cytoplasm
- Fatty acid biosynthesis
- Magnesium
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Transcription regulation
- Ubl conjugation
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| Golgi apparatus |
| axon |
| cytoplasmic stress granule |
| dendrite |
| neuronal cell body |
| nuclear speck |
| nucleotide-activated protein kinase complex |
| cytosol |
Sequence
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFFEMCASLITTLAR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 388 |
|
|||
|
|
G47012YE
G00912UN
G48414YA
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1289 | neurodegenerative disease | |
| DOID:12894 | Sjogren's syndrome | |
| DOID:12895 | keratoconjunctivitis sicca | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:12932 | endomyocardial fibrosis | |
| DOID:13087 | Lown-Ganong-Levine syndrome | |
| DOID:1324 | lung cancer | |
| DOID:1325 | bronchus cancer | |
| DOID:13250 | diarrhea | |
| DOID:13328 | diabetic cataract |
