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Sjogren's syndrome
Summary
- Synonym
-
- Sicca syndrome
- Sjogren syndrome
- xerodermosteosis
- Definition
- An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
- Super Class
- autoimmune disease of exocrine system
External Links
- Disease Ontology
- DOID:12894
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 348 | APOE | apolipoprotein E | |
| 831 | CAST | calpastatin | |
| 1234 | CCR5 | C-C motif chemokine receptor 5 | |
| 1493 | CTLA4 | cytotoxic T-lymphocyte associated protein 4 | |
| 1543 | CYP1A1 | cytochrome P450 family 1 subfamily A member 1 | |
| 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3187 | HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 | |
| 3557 | IL1RN | interleukin 1 receptor antagonist |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12775 | Ccr7 | C-C motif chemokine receptor 7 | |
| 14102 | Fas | Fas cell surface death receptor | |
| 16183 | Il2 | interleukin 2 | |
| 16184 | Il2ra | interleukin 2 receptor, alpha chain | |
| 16189 | Il4 | interleukin 4 | |
| 19143 | St14 | suppression of tumorigenicity 14 (colon carcinoma) | |
| 21803 | Tgfb1 | transforming growth factor, beta 1 | |
| 21825 | Thbs1 | thrombospondin 1 | |
| 24099 | Tnfsf13b | tumor necrosis factor (ligand) superfamily, member 13b | |
| 239611 | Muc19 | mucin 19 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P01374 | Lymphotoxin-alpha | |
| P01375 | Tumor necrosis factor | |
| P01909 | HLA class II histocompatibility antigen, DQ alpha 1 chain | |
| P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | |
| P01920 | HLA class II histocompatibility antigen, DQ beta 1 chain | |
| P02649 | Apolipoprotein E | |
| P04798 | Cytochrome P450 1A1 | |
| P05231 | Interleukin-6 | |
| P08670 | Vimentin | |
| P14780 | Matrix metalloproteinase-9 |
