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Integrin alpha-1

Summary

UniProt ID

P56199

Gene Symbol

ITGA1

Organism

Homo sapiens (human)

External Links

GlyConnect

1405

GlyGen

P56199

PubChem

P56199

The O-GlcNAc Database

P56199

RaftProt

P56199

O-GlcNAcAtlas

P56199

Annotation

Keyword

3D-structure
Calcium
Cell adhesion
Disulfide bond
Glycoprotein
Integrin
Magnesium
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

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GO Term
negative regulation of cell population proliferation
neuron projection morphogenesis
cell-cell adhesion
neutrophil chemotaxis
positive regulation of neuron apoptotic process
cell-matrix adhesion
vasodilation
cellular extravasation
integrin-mediated signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway

Displaying entries **1 - 10** of 11 in total

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GO Term
acrosomal vesicle
plasma membrane
membrane
extracellular exosome
perikaryon
focal adhesion
integrin complex
external side of plasma membrane
cell surface
basal part of cell

Displaying **all 5** entries
GO Term
collagen binding
metal ion binding
integrin binding
protein phosphatase binding
collagen binding involved in cell-matrix adhesion

Annotation information from UniProt.

Sequence

MAPRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
74	N-linked (GlcNAc...) asparagine			UniProt GlyGen
100	N-linked (GlcNAc...) asparagine	19159218	G14943SF G70232NH G70888PK G06247RL G80075MS G57776ZS G75418YA G86880BF G27947YN G79666IR G40834TG G45395BF G40926MX G08918WF G00912UN G83646BJ G27058EU G60033FS G80920RR G62765YT G85269DF	UniProt GlyGen
105	N-linked (GlcNAc...) asparagine	19159218	G26436YP	UniProt GlyGen
112	N-linked (GlcNAc...) asparagine		G30740WO G83646BJ G83460ZZ G08290VR G46503DX G25079LO G80920RR G73968GN G83633GK G62765YT G88891KO G31852PQ G96993FE G90575OW G41247ZX	UniProt GlyGen
217	N-linked (GlcNAc...) asparagine	19159218	G70232NH G75568BH G80075MS G57776ZS G77669RF G86880BF G27947YN G90382BL G80479JV G85282JO G20528HD G79666IR G92135MA G40834TG G45395BF G59324HL G07246CJ G85554PZ G20706XG G40926MX G14972EH G43223CG G08918WF G00912UN G27915IV G70441OD G87661QW G83646BJ G76295SF G15664MX G46691LC G04657PL G27058EU G60033FS G41071NU G72747WU G59626AS G80920RR G42124LM G90659AW G62765YT G95177YH G31852PQ G54010QB G84225JN	UniProt GlyGen
317	N-linked (GlcNAc...) asparagine		G81637OR G60967DT G80669SJ G39471UU G70232NH G55132BD G69521XL G35541EV G93718GY G13131HA G80075MS G57776ZS G29545VG G68490OW G86880BF G90382BL G85282JO G96577RX G79666IR G45395BF G07246CJ G14972EH G43223CG G08918WF G99966GV G70441OD G87661QW G83646BJ G27058EU G84452RH G41071NU G46902YN G80920RR G90659AW G62765YT G31852PQ G84225JN	UniProt GlyGen GlyConnect
341	N-linked (GlcNAc...) asparagine	19159218	G07810QS G29545VG G77669RF G80479JV G85282JO G04854VP G94470IW G45395BF G85554PZ G20706XG G10819WX G40926MX G08918WF G00912UN G49906RN G27915IV G92551JA G61256FT G87661QW G83646BJ G27058EU G43769HG G83460ZZ G10488MI G60033FS G41071NU G86182NS G70619PT G59626AS G80920RR G01485JJ G65184UU G42124LM G90659AW G62765YT G72790NZ G10486CT G95865ZB	UniProt GlyGen
402	N-linked (GlcNAc...) asparagine			UniProt GlyGen
418	N-linked (GlcNAc...) asparagine	19159218	G83460ZZ G01650EU G80920RR G37399XV G62765YT G90734RJ G28541PG G31852PQ G39446WN G39188ZX G41247ZX G57776ZU G02815KT G92050GC G28681TP G58001LT	UniProt GlyGen GlyConnect
425			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
CHL1 interactions	Homo sapiens
Integrin cell surface interactions	Homo sapiens
Laminin interactions	Homo sapiens
Other semaphorin interactions	Homo sapiens
Platelet Adhesion to exposed collagen	Homo sapiens
Smooth Muscle Contraction	Homo sapiens

Human Protein Atlas

ENSG00000213949

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements